Is Cleft Palate More Common In Other Countries?

Why is cleft palate so common in Asia?

Recently, Wu and colleagues discovered two genes from chromosome 4 among Asians—predominantly East Asians—result in a higher risk of nonsyndromic cleft palate when mothers were exposed to tobacco smoke three months prior to pregnancy until the first trimester..

What race has the most cleft palate?

Race—cleft lip and palate are more common in Asians and Native Americans than in African Americans (see Incidence and Prevalence section). Sex—males are more likely to have cleft lip with or without cleft palate; females are more likely to have cleft palate without cleft lip (see Incidence and Prevalence section).

Can cleft palate be prevented?

You can’t always prevent cleft lip and cleft palate in your baby. But there are things you can do to help reduce your baby’s chances of having these birth defects: Take folic acid. Before pregnancy, take a multivitamin with 400 micrograms of folic acid in it every day.

Every year, 7.9 million infants (approximately 6 percent of babies worldwide) are born with serious abnormalities. These can be related to the anatomy (such as clubfoot or cleft lip), chromosomal abnormalities (such as Down syndrome – Trisomy 21) or biochemical/genetic mutations (such as sickle-cell disease).

Which race has the most birth defects?

American Indians had the highest rates of lethal birth defects, followed by Asians, Hispanics, and blacks. The variation in rate of lethal birth defects among racial/ethnic groups may have been related to both incidence and survival.

What race is most likely to get Down syndrome?

Down syndrome has been reported in people of all races; no racial predilection is known. African American patients with Down syndrome have substantially shorter life spans than white patients with trisomy 21.

Where in the world is cleft palate most common?

The states with the highest and lowest rates were Maryland (21.46) and West Virginia (2.59), respectively. The United States cleft lip national rate averaged 7.75. Countries with the highest and lowest rates were Japan (19.05) and South Africa (3.13), respectively.

Why is cleft palate so common in India?

Substandard nutrition and a lack of prenatal care are known to be the likely reasons for these congenital disorders. “Significant efforts must be made to relieve the prevalent unmet need and strengthen health care services to meet the demand of new cases so that the surgical backlog does not grow,” Stewart added.

How common is cleft palate in the United States?

About 1 in every 1,600 babies is born with cleft lip with cleft palate in the United States. About 1 in every 2,800 babies is born with cleft lip without cleft palate in the United States. About 1 in every 1,700 babies is born with cleft palate in the United States.

At what age is cleft palate repair?

When is the right time for cleft palate surgery? Cleft palates are typically repaired between 8 and 12 months of age. Clefts of the soft palate can usually be repaired early (8 to 10 months of age). Clefts of the hard and soft palate are best repaired later (10 to 12 months of age).

Can you see cleft lip at 12 week scan?

This case demonstrates and emphasizes that early and accurate diagnosis of cleft lip and palate in the first trimester, as early as 12 weeks’ gestation, is a real possibility. It should be attempted at the time of ultrasound for first-trimester screening.

What increases risk of cleft palate?

Parents with a family history of cleft lip or cleft palate face a higher risk of having a baby with a cleft. Exposure to certain substances during pregnancy. Cleft lip and cleft palate may be more likely to occur in pregnant women who smoke cigarettes, drink alcohol or take certain medications. Having diabetes.